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Homologous recombination pathway gene variants identified by tumor-only sequencing assays in lung carcinoma patients
BACKGROUND: The homologous recombination (HR) repair pathway plays a key role in double-stranded DNA break repair, and germline HR pathway gene variants are associated with increased risk of several cancers, including breast and ovarian cancer. HR deficiency is also a therapeutically targetable phen...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326790/ https://www.ncbi.nlm.nih.gov/pubmed/37425424 http://dx.doi.org/10.21037/tlcr-22-749 |