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Downregulation of VEGFR2 signaling by cedrol abrogates VEGF‑driven angiogenesis and proliferation of glioblastoma cells through AKT/P70S6K and MAPK/ERK1/2 pathways

Cedrol is a sesquiterpene alcohol isolated from Cedrus atlantica, which has been traditionally used in aromatherapy and has anticancer, antibacterial and antihyperalgesic effects. One characteristic of glioblastoma (GB) is the overexpression of vascular endothelial growth factor (VEGF), which induce...

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Detalles Bibliográficos
Autores principales: Chang, Kai-Fu, Liu, Che-Yu, Huang, Ya-Chih, Hsiao, Chih-Yen, Tsai, Nu-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326829/
https://www.ncbi.nlm.nih.gov/pubmed/37427338
http://dx.doi.org/10.3892/ol.2023.13928