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Persistent biofluid small molecule alterations induced by Trypanosoma cruzi infection are not restored by antiparasitic treatment

Chagas Disease (CD), caused by Trypanosoma cruzi (T. cruzi) protozoa, is a complicated parasitic illness with inadequate medical measures for diagnosing infection and monitoring treatment success. To address this gap, we analyzed changes in the metabolome of T. cruzi-infected mice via liquid chromat...

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Detalles Bibliográficos
Autores principales: Dean, Danya A., Roach, Jarrod, vonBargen, Rebecca Ulrich, Xiong, Yi, Kane, Shelley S., Klechka, London, Wheeler, Kate, Sandoval, Michael Jimenez, Lesani, Mahbobeh, Hossain, Ekram, Katemauswa, Mitchelle, Schaefer, Miranda, Harris, Morgan, Barron, Sayre, Liu, Zongyuan, Pan, Chongle, McCall, Laura-Isobel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326868/
https://www.ncbi.nlm.nih.gov/pubmed/37425694
http://dx.doi.org/10.1101/2023.06.03.543565