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Multi-Attribute Monitoring Method for Process Development of Engineered Antibody for Site-Specific Conjugation

[Image: see text] Antibody drug conjugates, a class of biotherapeutic proteins, have been extensively developed in recent years, resulting in new approvals and improved standard of care for cancer patients. Among the numerous strategies of conjugating cytotoxic payloads to monoclonal antibodies, ins...

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Detalles Bibliográficos
Autores principales: Hines, Alistair R., Edgeworth, Matthew, Devine, Paul W. A., Shepherd, Samuel, Chatterton, Nicholas, Turner, Claire, Lilley, Kathryn S., Chen, Xiaoyu, Bond, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326913/
https://www.ncbi.nlm.nih.gov/pubmed/37265400
http://dx.doi.org/10.1021/jasms.3c00037