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Apigenin inhibits angiogenesis in retinal microvascular endothelial cells through regulating of the miR-140-5p/HDAC3-mediated PTEN/PI3K/AKT pathway

BACKGROUND: Diabetic retinopathy (DR) is a common cause of visual impairment. Apigenin has been shown to have antiangiogenic effects in various diseases. Our study aimed to investigate the role of apigenin in DR and elucidate the underlying mechanism. METHODS: Human retinal microvascular endothelial...

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Detalles Bibliográficos
Autores principales: Fu, Chaojun, Peng, Jun, Ling, Yanjun, Zhao, Hongqing, Zhao, Yongwang, Zhang, Xiuli, Ai, Min, Peng, Qinghua, Qin, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326941/
https://www.ncbi.nlm.nih.gov/pubmed/37415101
http://dx.doi.org/10.1186/s12886-023-03046-5