Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity

Dopaminergic neurons of the substantia nigra exist in a persistent state of vulnerability resulting from high baseline oxidative stress, high energy demand, and broad unmyelinated axonal arborizations. Impairments in the storage of dopamine compound this stress due to cytosolic reactions that transf...

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Detalles Bibliográficos
Autores principales: Bucher, Meghan L, Dunn, Amy R, Bradner, Joshua M, Egerton, Kristen Stout, Burkett, James P, Johnson, Michelle A, Miller, Gary W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326994/
https://www.ncbi.nlm.nih.gov/pubmed/37425736
http://dx.doi.org/10.1101/2023.06.26.546143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326994/
https://www.ncbi.nlm.nih.gov/pubmed/37425736
http://dx.doi.org/10.1101/2023.06.26.546143

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