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Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern

With the SARS-CoV-2 virus still circulating and evolving, there remains an outstanding question if variant-specific vaccines represent the optimal path forward, or if other strategies might be more efficacious towards providing broad protection against emerging variants. Here, we examine the efficac...

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Detalles Bibliográficos
Autores principales: Weidenbacher, Payton A.-B., Friedland, Natalia, Sanyal, Mrinmoy, Morris, Mary Kate, Do, Jonathan, Hanson, Carl, Kim, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326996/
https://www.ncbi.nlm.nih.gov/pubmed/37425802
http://dx.doi.org/10.1101/2023.06.27.546764