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Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches

The ability to sense and respond to intracellular metabolite levels enables cells to adapt to environmental conditions. Many prokaryotes use riboswitches – structured RNA elements usually located in the 5’ untranslated region of mRNAs – to sense intracellular metabolites and respond by modulating ge...

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Detalles Bibliográficos
Autores principales: Procknow, Rebecca R., Kennedy, Kristopher J., Kluba, Maxwell, Rodriguez, Lesley J., Taga, Michiko E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327014/
https://www.ncbi.nlm.nih.gov/pubmed/37425860
http://dx.doi.org/10.1101/2023.06.26.546531