Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition

The Resistance-Nodulation-Division (RND) efflux pump superfamily is pervasive among Gram-negative pathogens and contributes extensively to clinical antibiotic resistance. The opportunistic pathogen Pseudomonas aeruginosa contains 12 RND-type efflux systems, with four contributing to resistance inclu...

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Detalles Bibliográficos
Autores principales: Kavanaugh, Logan G., Mahoney, Andrew R., Dey, Debayan, Wuest, William M., Conn, Graeme L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327050/
https://www.ncbi.nlm.nih.gov/pubmed/37425949
http://dx.doi.org/10.1101/2023.03.24.533986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327050/
https://www.ncbi.nlm.nih.gov/pubmed/37425949
http://dx.doi.org/10.1101/2023.03.24.533986

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