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Loss of Bacteroides thetaiotaomicron bile acid altering enzymes impact bacterial fitness and the global metabolic transcriptome

Bacteroides thetaiotaomicron (B. theta) is a Gram-negative gut bacterium that encodes enzymes that alter the bile acid pool in the gut. Primary bile acids are synthesized by the host liver and are modified by gut bacteria. B. theta encodes two bile salt hydrolases (BSHs), as well as a hydroxysteroid...

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Detalles Bibliográficos
Autores principales: McMillan, Arthur S., Foley, Matthew H., Perkins, Caroline E., Theriot, Casey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327073/
https://www.ncbi.nlm.nih.gov/pubmed/37425690
http://dx.doi.org/10.1101/2023.06.27.546749