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Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum

Cryptosporidium parvum is an obligate intracellular parasite with a highly reduced mitochondrion that lacks the TCA cycle and the ability to generate ATP, making the parasite reliant on glycolysis. Genetic ablation experiments demonstrated that neither of the two putative glucose transporters CpGT1...

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Detalles Bibliográficos
Autores principales: Xu, Rui, Beatty, Wandy L., Greigert, Valentin, Witola, William H., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327089/
https://www.ncbi.nlm.nih.gov/pubmed/37425855
http://dx.doi.org/10.1101/2023.06.27.546703