CHARR efficiently estimates contamination from DNA sequencing data

DNA sample contamination is a major issue in clinical and research applications of whole genome and exome sequencing. Even modest levels of contamination can substantially affect the overall quality of variant calls and lead to widespread genotyping errors. Currently, popular tools for estimating th...

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Detalles Bibliográficos
Autores principales: Lu, Wenhan, Gauthier, Laura D., Poterba, Timothy, Giacopuzzi, Edoardo, Goodrich, Julia K., Stevens, Christine R., King, Daniel, Daly, Mark J., Neale, Benjamin M., Karczewski, Konrad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327099/
https://www.ncbi.nlm.nih.gov/pubmed/37425834
http://dx.doi.org/10.1101/2023.06.28.545801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327099/
https://www.ncbi.nlm.nih.gov/pubmed/37425834
http://dx.doi.org/10.1101/2023.06.28.545801

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