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Unveiling targeted cell-free DNA methylation regions through paired methylome analysis of tumor and normal tissues

Liquid biopsy analysis of cell-free DNA (cfDNA) has revolutionized cancer research by enabling non-invasive assessment of tumor-derived genetic and epigenetic changes. In this study, we conducted a comprehensive paired-sample differential methylation analysis (psDMR) on reprocessed methylation data...

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Detalles Bibliográficos
Autores principales: Li, Tingyi, Patel, Krupal B, Yu, Xiaoqing, Yao, Sijie, Wang, Liang, Chung, Christine H, Wang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327111/
https://www.ncbi.nlm.nih.gov/pubmed/37425680
http://dx.doi.org/10.1101/2023.06.27.546654