Fast and flexible joint fine-mapping of multiple traits via the Sum of Single Effects model

We introduce mvSuSiE, a multi-trait fine-mapping method for identifying putative causal variants from genetic association data (individual-level or summary data). mvSuSiE learns patterns of shared genetic effects from data, and exploits these patterns to improve power to identify causal SNPs. Compar...

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Detalles Bibliográficos
Autores principales: Zou, Yuxin, Carbonetto, Peter, Xie, Dongyue, Wang, Gao, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327118/
https://www.ncbi.nlm.nih.gov/pubmed/37425935
http://dx.doi.org/10.1101/2023.04.14.536893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327118/
https://www.ncbi.nlm.nih.gov/pubmed/37425935
http://dx.doi.org/10.1101/2023.04.14.536893

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