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GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disorder with limited therapeutic options. Insufficient understanding of driver mutations and poor fidelity of currently available animal models has limited the development of effective therapies. Since GATA1 deficient megakaryocytes...

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Detalles Bibliográficos
Autores principales: Gobbo, Francesca, Zingariello, Maria, Verachi, Paola, Falchi, Mario, Arciprete, Francesca, Martelli, Fabrizio, Peli, Angelo, Mazzarini, Maria, Vierstra, Jeff, Mead-Harvey, Carolyn, Dueck, Amylou C., Sarli, Giuseppe, Nava, Stefano, Sgalla, Giacomo, Richeldi, Luca, Migliaccio, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327123/
https://www.ncbi.nlm.nih.gov/pubmed/37425686
http://dx.doi.org/10.1101/2023.06.20.542249