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An engineered biosensor enables dynamic aspartate measurements in living cells

Intracellular levels of the amino acid aspartate are responsive to changes in metabolism in mammalian cells and can correspondingly alter cell function, highlighting the need for robust tools to measure aspartate abundance. However, comprehensive understanding of aspartate metabolism has been limite...

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Detalles Bibliográficos
Autores principales: Davidsen, Kristian, Marvin, Jonathan S, Aggarwal, Abhi, Brown, Timothy A, Sullivan, Lucas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327124/
https://www.ncbi.nlm.nih.gov/pubmed/37425831
http://dx.doi.org/10.1101/2023.06.27.546775