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CaBLAM! A high-contrast bioluminescent Ca(2+) indicator derived from an engineered Oplophorus gracilirostris luciferase

Ca(2+) plays many critical roles in cell physiology and biochemistry, leading researchers to develop a number of fluorescent small molecule dyes and genetically encodable probes that optically report changes in Ca(2+) concentrations in living cells. Though such fluorescence-based genetically encoded...

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Detalles Bibliográficos
Autores principales: Lambert, Gerard G., Crespo, Emmanuel L., Murphy, Jeremy, Boassa, Daniela, Luong, Selena, Celinskis, Dmitrijs, Venn, Stephanie, Hu, Junru, Sprecher, Brittany, Tree, Maya O., Orcutt, Richard, Heydari, Daniel, Bell, Aidan B., Torreblanca-Zanca, Albertina, Hakimi, Ali, Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute, Shaner, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327125/
https://www.ncbi.nlm.nih.gov/pubmed/37425712
http://dx.doi.org/10.1101/2023.06.25.546478