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The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix

Genetic background shifts the severity of muscular dystrophy. In mice, the DBA/2J strain confers a more severe muscular dystrophy phenotype, whereas the Murphy’s Roth Large (MRL) strain has “super-healing” properties that reduce fibrosis. A comparative analysis of the Sgcg null model of Limb Girdle...

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Detalles Bibliográficos
Autores principales: O’Brien, Joseph G., Willis, Alexander B., Long, Ashlee M., Kwon, Jason, Lee, GaHyun, Li, Frank, Page, Patrick G.T., Vo, Andy H., Hadhazy, Michele, Crosbie, Rachelle H., Demonbreun, Alexis R., McNally, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327155/
https://www.ncbi.nlm.nih.gov/pubmed/37425960
http://dx.doi.org/10.1101/2023.06.29.547098