Crystal structures reveal nucleotide-induced conformational changes in G motifs and distal regions in guanylate-binding protein 2

Guanylate-binding proteins (GBPs) are interferon-inducible GTPases that confer protective immunity against a variety of intracellular pathogens including bacteria, viruses, and protozoan parasites. GBP2 is one of the two highly inducible GBPs, yet the precise mechanisms underlying the activation and...

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Detalles Bibliográficos
Autores principales: Roy, Sayantan, Wang, Bing, Tian, Yuan, Yin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327160/
https://www.ncbi.nlm.nih.gov/pubmed/37425906
http://dx.doi.org/10.1101/2023.06.28.546747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327160/
https://www.ncbi.nlm.nih.gov/pubmed/37425906
http://dx.doi.org/10.1101/2023.06.28.546747

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