Cargando…

Crystal structures reveal nucleotide-induced conformational changes in G motifs and distal regions in guanylate-binding protein 2

Guanylate-binding proteins (GBPs) are interferon-inducible GTPases that confer protective immunity against a variety of intracellular pathogens including bacteria, viruses, and protozoan parasites. GBP2 is one of the two highly inducible GBPs, yet the precise mechanisms underlying the activation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roy, Sayantan, Wang, Bing, Tian, Yuan, Yin, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327160/ https://www.ncbi.nlm.nih.gov/pubmed/37425906 http://dx.doi.org/10.1101/2023.06.28.546747

Ejemplares similares

A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins
por: Kohler, Kristin M., et al.
Publicado: (2020)

Biophysical Analysis of Kindlin-3 Reveals an Elongated Conformation and Maps Integrin Binding to the Membrane-distal β-Subunit NPXY Motif
por: Yates, Luke A., et al.
Publicado: (2012)

Characterization of tomato protein kinases embedding guanylate cyclase catalytic center motif
por: Rahman, Hafizur, et al.
Publicado: (2020)

Integrative modeling of guanylate binding protein dimers
por: Schumann, Wibke, et al.
Publicado: (2023)

Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection
por: Koltes, James E., et al.
Publicado: (2015)

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
por: Winger, Jonathan A, et al.
Publicado: (2008)

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase
por: Allerston, Charles K., et al.
Publicado: (2013)

The Research of G–Motif Construction and Chirality in Deoxyguanosine Monophosphate Nucleotide Complexes
por: Zhu, Yanhong, et al.
Publicado: (2021)

Guanylate-Binding Protein 1: An Emerging Target in Inflammation and Cancer
por: Honkala, Alexander T., et al.
Publicado: (2020)

When human guanylate-binding proteins meet viral infections
por: Zhang, Rongzhao, et al.
Publicado: (2021)

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR
por: Csanády, László, et al.
Publicado: (2013)

Nucleotide binding is the critical regulator of ABCG2 conformational transitions
por: Gyöngy, Zsuzsanna, et al.
Publicado: (2023)

GABPα and CREB1 Binding to Double Nucleotide Polymorphisms of Their Consensus Motifs and Cooperative Binding to the Composite ETS ⇔ CRE Motif (ACCGGAAGTGACGTCA)
por: Assad, Nima, et al.
Publicado: (2019)

Guanylate-Binding Protein 2 Exerts GTPase-Dependent Anti-Ectromelia Virus Effect
por: Gao, Zhenzhen, et al.
Publicado: (2023)

Oncogenic Role of Guanylate Binding Protein 1 in Human Prostate Cancer
por: Zhao, Jing, et al.
Publicado: (2020)

Functional cross-species conservation of guanylate-binding proteins in innate immunity
por: Schelle, Luca, et al.
Publicado: (2022)

The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases
por: Li, Yichen, et al.
Publicado: (2022)

Guanylate-binding protein 1 modulates proteasomal machinery in ovarian cancer
por: Tailor, Dhanir, et al.
Publicado: (2023)

Single‐cell RNA‐seq reveals interferon‐induced guanylate‐binding proteins are linked with sarcopenia
por: Peng, Zhi, et al.
Publicado: (2022)

Different conformations and packing motifs in the crystal structures of four thiophene–carbohydrazide–pyridine derivatives
por: Garbutt, Jennifer L., et al.
Publicado: (2022)

IgG Conformer's Binding to Amyloidogenic Aggregates
por: Phay, Monichan, et al.
Publicado: (2015)

Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ
por: Tietzel, Illya, et al.
Publicado: (2009)

Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner
por: Britzen-Laurent, Nathalie, et al.
Publicado: (2010)

Insight into Temperature Dependence of GTPase Activity in Human Guanylate Binding Protein-1
por: Rani, Anjana, et al.
Publicado: (2012)

Guanylate-binding protein 1 participates in cellular antiviral response to dengue virus
por: Pan, Wen, et al.
Publicado: (2012)

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
por: Kravets, Elisabeth, et al.
Publicado: (2016)

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
por: Finethy, Ryan, et al.
Publicado: (2017)

Interferon-induced guanylate-binding proteins: Guardians of host defense in health and disease
por: Tretina, Kyle, et al.
Publicado: (2019)

Processing and secretion of guanylate binding protein‐1 depend on inflammatory caspase activity
por: Naschberger, Elisabeth, et al.
Publicado: (2017)

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
por: Place, David E., et al.
Publicado: (2021)

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2
por: Loschwitz, Jennifer, et al.
Publicado: (2023)

Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence
por: Sagot, Isabelle, et al.
Publicado: (2005)

Intracellular injection of guanyl nucleotides alters the serotonin- induced increase in potassium conductance in Aplysia neuron R15
Publicado: (1984)

CodingMotif: exact determination of overrepresented nucleotide motifs in coding sequences
por: Ding, Yang, et al.
Publicado: (2012)

Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma
por: Wang, Qiaoqi, et al.
Publicado: (2018)

Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments
por: Zhang, Xiaohua, et al.
Publicado: (2023)

Crystal Structure of the S. solfataricus Archaeal Exosome Reveals Conformational Flexibility in the RNA-Binding Ring
por: Lu, Changrui, et al.
Publicado: (2010)

Magnesium-binding architectures in RNA crystal structures: validation, binding preferences, classification and motif detection
por: Zheng, Heping, et al.
Publicado: (2015)

Sports Participation Promotes Beneficial Adaptations in the Erythrocyte Guanylate Nucleotide Pool in Male Athletes Aged 20–90 Years
por: Pospieszna, Barbara, et al.
Publicado: (2023)

Nucleotide binding database NBDB – a collection of sequence motifs with specific protein-ligand interactions
por: Zheng, Zejun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bdie0qmoe764814l51g1693gqh