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Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis

Gram-positive bacteria use SigI/RsgI-family sigma factor/anti-sigma factor pairs to sense and respond to cell wall defects and plant polysaccharides. In Bacillus subtilis this signal transduction pathway involves regulated intramembrane proteolysis (RIP) of the membrane-anchored anti-sigma factor Rs...

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Detalles Bibliográficos
Autores principales: Brogan, Anna P., Habib, Cameron, Hobbs, Samuel J., Kranzusch, Philip J., Rudner, David Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327162/
https://www.ncbi.nlm.nih.gov/pubmed/37425962
http://dx.doi.org/10.1101/2023.06.27.546760