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HOXDeRNA activates a cancerous transcription program and super-enhancers genome-wide
BACKGROUND: The origin and genesis of highly malignant and heterogenous glioblastoma brain tumors remain unknown. We previously identified an enhancer-associated long non-coding RNA, LINC01116 (named HOXDeRNA here), that is absent in the normal brain but is commonly expressed in malignant glioma. HO...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327164/ https://www.ncbi.nlm.nih.gov/pubmed/37425921 http://dx.doi.org/10.1101/2023.06.30.547275 |