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HOXDeRNA activates a cancerous transcription program and super-enhancers genome-wide

BACKGROUND: The origin and genesis of highly malignant and heterogenous glioblastoma brain tumors remain unknown. We previously identified an enhancer-associated long non-coding RNA, LINC01116 (named HOXDeRNA here), that is absent in the normal brain but is commonly expressed in malignant glioma. HO...

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Detalles Bibliográficos
Autores principales:	Deforzh, Evgeny, Kharel, Prakash, Karelin, Anton, Ivanov, Pavel, Krichevsky, Anna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327164/ https://www.ncbi.nlm.nih.gov/pubmed/37425921 http://dx.doi.org/10.1101/2023.06.30.547275

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