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Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus

Staphylococcus aureus only synthesizes straight-chain or branched-chain saturated fatty acids (SCFAs or BCFAs) via the type II fatty acid synthesis (FASII) pathway, but as a highly adaptive pathogen, S. aureus can also utilize host-derived exogenous fatty acids (eFAs), including SCFAs and unsaturate...

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Detalles Bibliográficos
Autores principales: Pruitt, Emily L., Zhang, Rutan, Ross, Dylan H., Ashford, Nathaniel K., Chen, Xi, Alonzo, Francis, Bush, Matthew F., Werth, Brian J., Xu, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327171/
https://www.ncbi.nlm.nih.gov/pubmed/37425828
http://dx.doi.org/10.1101/2023.06.29.547085