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Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations

Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting interventions for treating cancer patients. Moreover, compensatory grow...

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Detalles Bibliográficos
Autores principales: Martell, Emma, Kuzmychova, Helgi, Senthil, Harshal, Kaul, Esha, Chokshi, Chirayu R., Venugopal, Chitra, Anderson, Christopher M., Singh, Sheila K., Sharif, Tanveer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327182/
https://www.ncbi.nlm.nih.gov/pubmed/37420311
http://dx.doi.org/10.1186/s40478-023-01604-y