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Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations
Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting interventions for treating cancer patients. Moreover, compensatory grow...
Autores principales: | Martell, Emma, Kuzmychova, Helgi, Senthil, Harshal, Kaul, Esha, Chokshi, Chirayu R., Venugopal, Chitra, Anderson, Christopher M., Singh, Sheila K., Sharif, Tanveer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327182/ https://www.ncbi.nlm.nih.gov/pubmed/37420311 http://dx.doi.org/10.1186/s40478-023-01604-y |
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