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Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters

Hybrid immunity to SARS-CoV-2 provides superior protection to re-infection. We performed immune profiling studies during breakthrough infections in mRNA-vaccinated hamsters to evaluate hybrid immunity induction. mRNA vaccine, BNT162b2, was dosed to induce binding antibody titers against ancestral sp...

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Detalles Bibliográficos
Autores principales: García-Bernalt Diego, Juan, Singh, Gagandeep, Jangra, Sonia, Handrejk, Kim, Laporte, Manon, Chang, Lauren A., El Zahed, Sara S., Pache, Lars, Chang, Max W., Warang, Prajakta, Aslam, Sadaf, Mena, Ignacio, Webb, Brett T., Benner, Christopher, García-Sastre, Adolfo, Schotsaert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327228/
https://www.ncbi.nlm.nih.gov/pubmed/37425792
http://dx.doi.org/10.1101/2023.05.22.541294