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A note on p-value multiple-testing adjustment for two-step genome-wide gene-environment interactions scans
Two-step testing is the state-of-the art approach for performing genome-wide interaction scans (GWIS). It is computationally efficient and yields higher power than standard single-step-based GWIS for virtually all biologically plausible scenarios. However, while two-step tests control the genome-wid...
Autores principales: | Lewinger, Juan Pablo, Kawaguchi, Eric S., Gauderman, W. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327251/ https://www.ncbi.nlm.nih.gov/pubmed/37425767 http://dx.doi.org/10.1101/2023.06.27.23291946 |
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