Differential DNA Methylation in the Brain as Potential Mediator of the Association between Traffic-related PM(2.5) and Neuropathology Markers of Alzheimer’s Disease

INTRODUCTION: Growing evidence indicates fine particulate matter (PM(2.5)) as risk factor for Alzheimer’s’ disease (AD), but the underlying mechanisms have been insufficiently investigated. We hypothesized differential DNA methylation (DNAm) in brain tissue as potential mediator of this association....

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Detalles Bibliográficos
Autores principales: Li, Zhenjiang, Liang, Donghai, Ebelt, Stefanie, Gearing, Marla, Kobor, Michael S., Konwar, Chaini, Maclsaac, Julie L, Dever, Kristy, Wingo, Aliza, Levey, Allan, Lah, James J., Wingo, Thomas, Huels, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327281/
https://www.ncbi.nlm.nih.gov/pubmed/37425713
http://dx.doi.org/10.1101/2023.06.30.23292085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327281/
https://www.ncbi.nlm.nih.gov/pubmed/37425713
http://dx.doi.org/10.1101/2023.06.30.23292085

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