Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs

BACKGROUND: Biomarker discovery in colorectal cancer has mostly focused on methylation patterns in normal and colorectal tumor tissue, but adenomas remain understudied. Therefore, we performed the first epigenome-wide study to profile methylation of all three tissue types combined and to identify di...

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Detalles Bibliográficos
Autores principales: Janssens, Katleen, Neefs, Isabelle, Ibrahim, Joe, Schepers, Anne, Pauwels, Patrick, Peeters, Marc, Van Camp, Guy, Op de Beeck, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327366/
https://www.ncbi.nlm.nih.gov/pubmed/37415235
http://dx.doi.org/10.1186/s13148-023-01516-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327366/
https://www.ncbi.nlm.nih.gov/pubmed/37415235
http://dx.doi.org/10.1186/s13148-023-01516-7

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