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Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments

Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune system's T-cells to recognize and attack tumor cells. T-cells are isolated from patients and modified to target tumo...

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Detalles Bibliográficos
Autores principales: Dagar, Gunjan, Gupta, Ashna, Masoodi, Tariq, Nisar, Sabah, Merhi, Maysaloun, Hashem, Sheema, Chauhan, Ravi, Dagar, Manisha, Mirza, Sameer, Bagga, Puneet, Kumar, Rakesh, Akil, Ammira S. Al-Shabeeb, Macha, Muzafar A., Haris, Mohammad, Uddin, Shahab, Singh, Mayank, Bhat, Ajaz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327392/
https://www.ncbi.nlm.nih.gov/pubmed/37420216
http://dx.doi.org/10.1186/s12967-023-04292-3