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PanGraph: scalable bacterial pan-genome graph construction

The genomic diversity of microbes is commonly parameterized as SNPs relative to a reference genome of a well-characterized, but arbitrary, isolate. However, any reference genome contains only a fraction of the microbial pangenome, the total set of genes observed in a given species. Reference-based a...

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Detalles Bibliográficos
Autores principales: Noll, Nicholas, Molari, Marco, Shaw, Liam P., Neher, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327495/
https://www.ncbi.nlm.nih.gov/pubmed/37278719
http://dx.doi.org/10.1099/mgen.0.001034