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Islet hypoplasia of adult offspring rats caused by intrauterine chronic hypoxia is compensated by up-regulation of INS and PDX-1

Background: Intrauterine chronic hypoxia (ICH) can lead to pancreatic dysmetabolism in offspring. This study aimed to determine the changes in islet function of offspring through a rat ICH model and detect the factors affecting islet function. Methods: Twenty couples of healthy Sprague – Dawley adul...

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Detalles Bibliográficos
Autores principales: Chen, Tianfeng, Xiao, Yang, Xu, Shaodan, Ke, Helin, Li, Shilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327515/
https://www.ncbi.nlm.nih.gov/pubmed/37409484
http://dx.doi.org/10.1080/19382014.2023.2231610