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Islet hypoplasia of adult offspring rats caused by intrauterine chronic hypoxia is compensated by up-regulation of INS and PDX-1
Background: Intrauterine chronic hypoxia (ICH) can lead to pancreatic dysmetabolism in offspring. This study aimed to determine the changes in islet function of offspring through a rat ICH model and detect the factors affecting islet function. Methods: Twenty couples of healthy Sprague – Dawley adul...
Autores principales: | Chen, Tianfeng, Xiao, Yang, Xu, Shaodan, Ke, Helin, Li, Shilin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327515/ https://www.ncbi.nlm.nih.gov/pubmed/37409484 http://dx.doi.org/10.1080/19382014.2023.2231610 |
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