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Hyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP(3)-PKC signalling pathway

CONTEXT: Hyperoside (Hyp), one of the active flavones from Rhododendron (Ericaceae), has beneficial effects against cerebrovascular disease. However, the effect of Hyp on vasodilatation has not been elucidated. OBJECTIVE: To explore the effect of Hyp on vasodilatation in the cerebral basilar artery...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Jiang, Chenchen, Xu, Hanghang, Wu, Jiangping, Lu, Jiajun, He, Yuxiang, Yin, Xiuyun, Chen, Zhuo, Cao, Di, Shen, Xuebin, Hou, Xuefeng, Han, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327524/
https://www.ncbi.nlm.nih.gov/pubmed/37410551
http://dx.doi.org/10.1080/13880209.2023.2228379