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Proanthocyanidins induce analgesic and anxiolytic effects in spared nerve injured mice by decreasing in vivo firing rate of pyramidal cells in the insular cortex

Neuropathic pain is one of the most common symptoms of clinical pain that often accompanied by severe emotional changes such as anxiety. However, the treatment for comorbidity of chronic pain and anxiety is limited. Proanthocyanidins (PACs), a group of polyphenols enriched in plants and foods, have...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Si, Hua-Xing, Zhu, Da-Yu, Xing, Ke-Ke, Wang, Jian, Cao, Ting-Ting, Zhao, Han, Liu, Xiao-Die, Zhang, Ming-Ming, Chen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327562/
https://www.ncbi.nlm.nih.gov/pubmed/37426072
http://dx.doi.org/10.3389/fnmol.2023.1174125