Tocilizumab improves clinical outcome in patients with active corticosteroid-resistant moderate-to-severe Graves’ orbitopathy: an observational study

BACKGROUND: Graves’ orbitopathy (GO) is an autoimmune disorder affecting the orbital fat and muscles. A significant role of IL-6 in the pathogenesis of GO has been described and tocilizumab (TCZ), an IL-6 inhibitor targeting IL-6R has been given in some patients. The aim of our case study was to eva...

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Detalles Bibliográficos
Autores principales: Boutzios, Georgios, Chatzi, Sofia, Goules, Andreas V., Mina, Areti, Charonis, George C., Vlachoyiannopoulos, Panayiotis G., Tzioufas, Athanasios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327634/
https://www.ncbi.nlm.nih.gov/pubmed/37424868
http://dx.doi.org/10.3389/fendo.2023.1186105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327634/
https://www.ncbi.nlm.nih.gov/pubmed/37424868
http://dx.doi.org/10.3389/fendo.2023.1186105

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