NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation

The colon epithelium is a primary point of interaction with the microbiome and is regenerated by a few rapidly cycling colonic stem cells (CSCs). CSC self-renewal and proliferation are regulated by growth factors and the presence of bacteria. However, the molecular link connecting the diverse inputs...

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Detalles Bibliográficos
Autores principales: van der Post, Sjoerd, Birchenough, George M.H., Held, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327654/
https://www.ncbi.nlm.nih.gov/pubmed/33826887
http://dx.doi.org/10.1016/j.celrep.2021.108949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327654/
https://www.ncbi.nlm.nih.gov/pubmed/33826887
http://dx.doi.org/10.1016/j.celrep.2021.108949

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