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Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest

Cardiac arrest (CA) causes high mortality due to multi-system organ damage attributable to ischemia-reperfusion injury. Recent work in our group found that among diabetic patients who experienced cardiac arrest, those taking metformin had less evidence of cardiac and renal damage after cardiac arres...

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Detalles Bibliográficos
Autores principales: Rutledge, Cody A., Lagranha, Claudia, Chiba, Takuto, Redding, Kevin, Stolz, Donna B., Goetzman, Eric, Sims-Lucas, Sunder, Kaufman, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327679/
https://www.ncbi.nlm.nih.gov/pubmed/37425219
http://dx.doi.org/10.1016/j.jmccpl.2023.100034