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Using Microfluidic Chip and Allele-Specific PCR to Rapidly Identify Drug Resistance-Associated Mutations of Mycobacterium tuberculosis

BACKGROUND: The currently used conventional susceptibility testing for drug-resistant Mycobacterium tuberculosis (M.TB) is limited due to being time-consuming and having low efficiency. Herein, we propose the use of a microfluidic-based method to rapidly detect drug-resistant gene mutations using Ko...

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Detalles Bibliográficos
Autores principales: Chen, Shan, Liu, Houming, Li, Tianpin, Lai, Wenjie, Liu, Lei, Xu, Youchun, Qu, Jiuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327919/
https://www.ncbi.nlm.nih.gov/pubmed/37424666
http://dx.doi.org/10.2147/IDR.S410779