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Monitoring α-synuclein Aggregation Induced by Preformed α-synuclein Fibrils in an In Vitro Model System

Parkinson’s disease (PD) is characterized by the presence of α-synuclein (α-syn) inclusions in the brain and the degeneration of dopamine-producing neurons. There is evidence to suggest that the progression of PD may be due to the prion-like spread of α-syn aggregates, so understanding and limiting...

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Detalles Bibliográficos
Autores principales: Kim, Beom Jin, Noh, Hye Rin, Jeon, Hyongjun, Park, Sang Myun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327928/
https://www.ncbi.nlm.nih.gov/pubmed/37403223
http://dx.doi.org/10.5607/en23007