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Intracellular Loop in the Brain Isoforms of Anoctamin 2 Channels Regulates Calcium-dependent Activation

Anoctamin 2 (ANO2 or TMEM16B), a calcium-activated chloride channel (CaCC), performs diverse roles in neurons throughout the central nervous system. In hippocampal neurons, ANO2 narrows action potential width and reduces postsynaptic depolarization with high sensitivity to Ca(2+) at relatively fast...

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Detalles Bibliográficos
Autores principales: Lee, Dongsu, Lim, Hocheol, Lee, Jungryun, Ha, Go Eun, No, Kyoung Tai, Cheong, Eunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327929/
https://www.ncbi.nlm.nih.gov/pubmed/37403222
http://dx.doi.org/10.5607/en22045