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Ubiquitous Luciferase Expression in “Firefly Rats” Does Not Alter the Pancreatic Islet Morphology, Metabolism, and Function

“Firefly rats” ubiquitously express the luciferase reporter gene under the control of constitutively active ROSA26 promoter in inbred Lewis rats. Due to the minimal immunogenicity of luciferase, wide applications of Firefly rats have been reported in solid organ/cell transplantation studies for in v...

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Detalles Bibliográficos
Autores principales: Gonzalez, Nelson, Kato, Hiroyuki, Tixi, Wilma, Ortiz, Jose, Orr, Chris, Shih, Hung-Ping, Ku, Hsun Teresa, Yee, Jiing-Kuan, Kandeel, Fouad, Mullen, Yoko, Kobayashi, Eiji, Komatsu, Hirotake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328002/
https://www.ncbi.nlm.nih.gov/pubmed/37345228
http://dx.doi.org/10.1177/09636897231182497