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Radioactive (125)I Seed Inhibits Cell Migration and Invasion and Promotes Apoptosis by Inactivating the VEGFR2 Signaling Pathway in Cholangiocarcinoma

OBJECTIVES: To investigate the potential mechanisms of (125)I seed implantation therapeutic treatment on inactivating the VEGFR2/PI3K/AKT pathway in cholangiocarcinoma. METHODS: The human cholangiocarcinoma cell lines HCCC-9810 and HuCCT1 were purchased for in vitro studies. The BALB/c nude mice wer...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Zheng, Jiaping, Yao, Hongxiang, Wang, Binbing, Zhang, Zhewei, Shao, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328048/
https://www.ncbi.nlm.nih.gov/pubmed/37424703
http://dx.doi.org/10.1177/15593258231187348