Energetic landscape of polycystin channel gating

Members of the polycystin family (PKD2 and PKD2L1) of transient receptor potential (TRP) channels conduct Ca(2+) and depolarizing monovalent cations. Variants in PKD2 cause autosomal dominant polycystic kidney disease (ADPKD) in humans, whereas loss of PKD2L1 expression causes seizure susceptibility...

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Detalles Bibliográficos
Autores principales: Ng, Leo CT, Harris, Brandon J, Larmore, Megan, Ta, My C, Vien, Thuy N, Tokars, Valerie L, Yarov‐Yarovoy, Vladimir, DeCaen, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328073/
https://www.ncbi.nlm.nih.gov/pubmed/37158562
http://dx.doi.org/10.15252/embr.202356783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328073/
https://www.ncbi.nlm.nih.gov/pubmed/37158562
http://dx.doi.org/10.15252/embr.202356783

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