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LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity

The establishment of axon‐dendrite polarity is fundamental for radial migration of neurons, cortical patterning, and formation of neuronal circuits. Here, we show that the receptor tyrosine kinases, Ltk and Alk, are required for proper neuronal polarization. In isolated primary mouse embryonic neuro...

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Detalles Bibliográficos
Autores principales: Christova, Tania, Ho, Stephanie KY, Liu, Ying, Gill, Mandeep, Attisano, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328079/
https://www.ncbi.nlm.nih.gov/pubmed/37291945
http://dx.doi.org/10.15252/embr.202356937