Cargando…

The rs1800469 T/T and rs1800470 C/C genotypes of the TGFB1 gene confer protection against diabetic retinopathy in a Southern Brazilian population

The transforming growth factor beta 1 (TGFB1) is a pro-inflammatory cytokine that plays a key role in the mechanisms of angiogenesis and breakdown of the blood-retina barrier, which are implicated in the pathogenesis of diabetic retinopathy (DR). Polymorphisms in the TGFB1 gene have been associated...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Aline Rodrigues, Dieter, Cristine, Canani, Luís Henrique, Assmann, Taís Silveira, Crispim, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328150/
https://www.ncbi.nlm.nih.gov/pubmed/37418683
http://dx.doi.org/10.1590/1678-4685-GMB-2022-0247