Silencing of long noncoding RNA X-inactive specific transcript alleviates Aβ1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization

OBJECTIVES: This experimental study aims to investigate the role of long noncoding RNA X-inactive specific transcript (lncRNA XIST) in the microglial polarization and microglia-mediated neurotoxicity in Alzheimer’s disease (AD). METHODS: The levels of XIST and microRNA-107 (miR-107) were detected by...

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Detalles Bibliográficos
Autores principales: Zhao, Kun-Peng, Wang, Xin-Yu, Shao, Mei-Qi, He, Chen-Yang, Yuan, Fu-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328177/
https://www.ncbi.nlm.nih.gov/pubmed/37400958
http://dx.doi.org/10.1177/03946320231184988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328177/
https://www.ncbi.nlm.nih.gov/pubmed/37400958
http://dx.doi.org/10.1177/03946320231184988

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