Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation

A history of infection has been linked with increased risk of acute myeloid leukaemia (AML) and related myelodysplastic syndromes (MDS). Furthermore, AML and MDS patients suffer frequent infections because of disease-related impaired immunity. However, the role of infections in the development and p...

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Detalles Bibliográficos
Autores principales: Trova, Sandro, Lin, Fei, Lomada, Santosh, Fenton, Matthew, Chauhan, Bhavini, Adams, Alexandra, Puri, Avani, Di Maio, Alessandro, Wieland, Thomas, Sewell, Daniel, Dick, Kirstin, Wiseman, Daniel, Wilks, Deepti P., Goodall, Margaret, Drayson, Mark T., Khanim, Farhat L., Bunce, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328239/
https://www.ncbi.nlm.nih.gov/pubmed/37418424
http://dx.doi.org/10.1371/journal.pone.0288162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328239/
https://www.ncbi.nlm.nih.gov/pubmed/37418424
http://dx.doi.org/10.1371/journal.pone.0288162

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