Cargando…
Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation
A history of infection has been linked with increased risk of acute myeloid leukaemia (AML) and related myelodysplastic syndromes (MDS). Furthermore, AML and MDS patients suffer frequent infections because of disease-related impaired immunity. However, the role of infections in the development and p...
Autores principales: | Trova, Sandro, Lin, Fei, Lomada, Santosh, Fenton, Matthew, Chauhan, Bhavini, Adams, Alexandra, Puri, Avani, Di Maio, Alessandro, Wieland, Thomas, Sewell, Daniel, Dick, Kirstin, Wiseman, Daniel, Wilks, Deepti P., Goodall, Margaret, Drayson, Mark T., Khanim, Farhat L., Bunce, Christopher M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328239/ https://www.ncbi.nlm.nih.gov/pubmed/37418424 http://dx.doi.org/10.1371/journal.pone.0288162 |
Ejemplares similares
-
Bacillus anthracis’ PA(63) Delivers the Tumor Metastasis Suppressor Protein NDPK-A/NME1 into Breast Cancer Cells
por: Felix, Ina, et al.
Publicado: (2020) -
Hypoxia Triggers Major Metabolic Changes in AML Cells without Altering Indomethacin-Induced TCA Cycle Deregulation
por: Lodi, Alessia, et al.
Publicado: (2010) -
Does the pursuit of scientific excellence serve or hamper translational medical research: an historical perspective from hematological malignancies
por: Bunce, Chris M., et al.
Publicado: (2022) -
Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing
por: Jiang, Yao, et al.
Publicado: (2021) -
Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity
por: Chatterjee, Anupriya, et al.
Publicado: (2020)